Year |
Event |
---|---|
March 2020 |
Morphoplant receives approval to handle microorganisms of biosafety level 2 (BioStoffV) |
March 2018 |
Salt-coated ultrahydrophilic implants receive CE-certification with the assistance of Morphoplants team |
October 2017 |
Morphoplants hydrophilic surface preservation technology has been successfully implemented in a fully-automatic production unit for the industrial-scale application of this techique |
September 2016 |
Asset purchase agreement between Morphoplant and one of the leading implant companies regarding Morphoplants hydrophilic surface preservation technology |
September 2014 |
Collaboration project between Morphoplant, BirdC and TU Wien has been successfully finished. A GMP-compliant production preocess for BMP-2 has been established |
August 2014 |
Successfull recombinant production of stem cell homing factor SDF-1 |
May 2014 |
Bioactive BMP-2 and VEGF have been incorporated into electro-spun PDLLA nano-composites fleeces. These fleeces might mimic the native extracellular matrix of bone tissue, stimulating angiogenesis and osteogenesis |
January 2013 |
Development of an fully automated etching- and dry packaging robot in collaboration with an equipment manufacturer |
August 2012 |
First preclinical in vivo-studies on VEGF and VEGF/ BMP-2 coated bone replacement implants |
June 2012 |
Development of a biocompatible bone glue |
October 2011 |
Morphoplant in collaboration with Bird-C/ Vienna and Technical University Vienna receives grand for the development of a GMP-compliant production process for BMP-2/ VEGF using Bird-C's proprietary bacterial ghost technology |
September 2011 |
BMBF funding of "BioMin" project - Functionalized mineral surface by immobilization of growth stimulating proteins |
March 2010 |
First preclinical in vivo-studies reveal strong stimulation of bone and osteoid ongrowth for ultrahydrophilic and rhBMP-2 coated titan-plasma-sprayed surfaces |
May 2009 |
Morphoplant moves to larger laboratory space at the BioMedizinZentrum Ruhr in Bochum/ Germany |
February 2009 |
First preclinical in vivo-studies in cooperation with SpineWelding AG, Schlieren/ Switzerland proofing rhBMP-2-coated PDLLA/ Algisorb-membranes suitable as drug delivery devices |
December 2008 |
First clinical pilot study using rhBMP-2 coated bone replacement materials |
January 2007 |
First preclinical in vivo-studies demonstrate strongly enhanced bone growth for rhBMP-2 coated phycogenic bone replacement materials using Morphoplants coating technology as well as for foamed rhBMP2/Poly-(D,L)-Lactide moulds |
August 2006 |
First systematic preclinical in vivo-studies corroborating superior effects of Morphoplants ultrahydrophilic and rhBMP-2 coated dental implant SLA-surfaces |
Februar 2006 |
AiF funding of "Boneadapt" project - Production of BMP-2 loaded osteoinductive ceramic bone replacement materials |
October 2004 |
Preclinical in vivo-studies prooving high biological activity of Morphoplants rhBMP-2 |
June 2004 |
Morphoplant receives funding within "NRW/ EU Ziel 2-Programm 2000-2006" |
May 2003 |
Moving into research laboratories located at Ruhr-University Bochum |
December 2002 |
Morphoplant was founded as a spin-off of the University Duisburg-Essen |